How does stem cell therapy effectively treat autoimmune diseases?
There are four critical functions that the Mesenchymal Stem Cells used in our stem cell therapy treatments perform in the body, and these are vital to the treatment of autoimmune disorders:
- Reduce Inflammation
- Modulate the immune system
- Reduce scaring
- Help your body regenerate
These four functions are critical in effectively treating autoimmune diseases. It is important to remember that chronic inflammation is the root cause of many serious illnesses and diseases. Chronic inflammation can cause DNA damage and has been known to lead to cancer. For instance, people with IBS or Chron’s Disease have an increased risk of colon cancer. According to an article published by The National Institutes of Health: “MSCs inhibit leukocytes by blocking their pro-inflammatory factor expression, resulting in decreasing levels of proinflammatory cytokine and leukocyte cell recruitment at the site of damage.”
In plain English - Mesenchymal stem cells reduce dangerous inflammation.
Modulating the immune system is the second of the critical functions of Mesenchymal stem cells. Here is an excerpt from another article published by The National Institutes of Health that sheds light on the ability of MSCs to regulate the immune system:
“Mesenchymal stem cell (MSC) immunosuppressive properties offer a potentially attractive therapeutic modality for autoimmune diseases. MSC inhibit virtually all types of immune responses in vitro and prevent the induction of disease in several experimental models of autoimmunity.”
The third function of Mesenchymal stem cells is the reduction of scarring. Many patients do not understand the risk associated with scarring or even that scarring occurs in autoimmune diseases. One of the significant risks of autoimmune disease is that it may cause a scar that ends in pathological fibrosis. This is defined by the accumulation of excess extracellular matrix components. When highly progressive this fibrotic process leads to organ failure and death. Fibrosis has the potential to affect nearly every tissue in the body of a person suffering from an autoimmune disease.
Mesenchymal stem cells and their derived products such as exosomes and extravesicles have shown a therapeutic ability to reduce scarring. These cells have been so efficient in the treatment of scarring and open wounds that the FDA has approved them for treating non-healing diabetic wounds.
The fourth function of Mesenchymal Stem Cells is that they help regenerate tissue. Autoimmune Disorders often result in the damage of connective tissue. These tissues are found throughout the body in tissue, joints, and vital organs. Damaged tissue in joints causes pain, discomfort, and limited mobility. Damaged tissue in vital organs can result in the death of the individual. There are more than eighty autoimmune diseases that can be treated with stem cell therapy at our lab and treatment center in Colombia, South America. We specialize in treating autoimmune diseases and are considered by many as the top stem cell therapy clinic in the World for the treatment of patients with autoimmune conditions.